Cancer genome and Immune system regulation

Our lab focuses on studying gene regulation in viral associated cancers (e.g. EBV and HBV related tumors), autoimmune disorders (e.g. Rheumatoid Arthritis), and infectious diseases (e.g. COVID-19). We utilize biological assays and computational models to identify novel biological pathways, new host-pathogen interactions and regulatory RNAs (e.g. enhancer RNAs and circular RNAs) that could trigger disease. 

We are exploiting single cell and bulk high throughput sequencing data (e.g. RNA-seq, ChIP-seq, ATAC-seq, Hi-C) using machine learning tools to guide experiments and treatments.